Cet anticorps anti-SARS-CoV-2 Nucleocapsid est un anticorps Souris Monoclonal détectant SARS-CoV-2 Nucleocapsid dans ELISA et WB. Adapté pour SARS Coronavirus-2 (SARS-CoV-2).
N° du produit ABIN6952935
Aperçu rapide pour SARS-CoV-2 Nucleocapsid anticorps (ABIN6952935)
SARS-CoV-2 N
Reactivité: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV)
ELISA, IF
Hôte: Human
Monoclonal
CR3018 (03-018)
unconjugated
Recombinant Antibody
Indications d'application
WB(1:500-2000), ELISA(1:500-1000)
Restrictions
For Research Use only
Format
Liquid
Concentration
≥ 1 mg/mL
Buffer
0.01M PBS( pH 7.4) with 0.1 % Proclin300
Agent conservateur
ProClin
Précaution d'utilisation
This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Antigène
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
Autre désignation
SARS-CoV-2 Nucleocapsid Protein
Classe de substances
Viral Protein
Sujet
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.